DPCstruct | MC8590

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)96 ± 7 aa
Standard deviation of domain lengths6.82
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.93
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)46.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V9VK75 3-99 RVNIQAPPNLSAPYYDELLDAGINDWGGVSPLTPDFINPEKPWPHLEQLRARTEAQGFKLEARLPVYPEFLSRALDRPGLLRERVQS…
K0B5W4 197-286 SRIIMPKMNIQIPPNLSPRSYQSFLSVGINDWGGISPLTPDFVNPEFSWPEINRVEENSKQAGFDLKCRFPIYPEFFSFISKELQEK…
A0A7C0X205 65-165 None
A0A1V5ZCC0 216-323 None
A0A523ARY0 2-83 None
A0A843DPA6 14-102 None
A0A812AB96 19-106 None
A0A066YRH7 288-384 None
A0A383W8E6 64-165 None
A0A5E4IKI4 1-91 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.