DPCstruct | MC8549

Metacluster Properties and Pfam Annotations

Number of structural domains343
Mean domain length (aa)120 ± 23 aa
Standard deviation of domain lengths23.25
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.50
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)25.68
Pfam Score98.88
Assigned Pfam label(s) CL0125- PF16211- CL0012- CL0020- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4KSE2 19-142 None
A0A0D7BU64 17-142 None
A0A5E4FUF8 75-203 None
A0A1M2V9L9 207-329 None
A0A4P9XQP7 2-113 None
A0A7S1AYD9 34-159 None
A0A0L6UCN0 75-183 None
A0A1S3CLF8 56-175 None
A0A2P5YIH2 5-121 None
A0A5N6RJT9 358-496 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.