DPCstruct | MC8549

Metacluster Properties and Pfam Annotations

Number of structural domains343
Mean domain length (aa)120 ± 23 aa
Standard deviation of domain lengths23.25
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.50
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)25.68
Pfam Score98.88
Assigned Pfam label(s) CL0125- PF16211- CL0012- CL0020- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q22979 1-65 MSIMNSFVNDVFERIAAEASRLAHYNKRSTISSREIQTAVRLILPGELAKNAVSEGTNAVTKYTS
A0A2A2J8Q4 59-186 MESSSGVDIRYQFSKMDEDNEVGLPQKGLNMIMKDAIPEMRIANESREIFNNCCVEFIKYISREAQQISGNDQRKTIYHEHVQKALQ…
S7RJI5 91-229 None
A0A5D3CS91 1-117 None
A0A1I8IDS8 458-563 None
F6QT13 1-65 None
Q2HW83 21-101 None
A0A0D3GZR7 3-159 None
A0A4S4D4U6 280-398 None
A0A194VTP1 2-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.