DPCstruct | MC8538

Metacluster Properties and Pfam Annotations

Number of structural domains464
Mean domain length (aa)155 ± 24 aa
Standard deviation of domain lengths23.59
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.14
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.66
Pfam Score81.80
Assigned Pfam label(s) PF05033- CL0489- CL0652- CL0010- PF11907

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A847MBE6 5-148 GEIPGIKVGQLFANRRELHDSGVHRPLQAGICGSADRGAESVVLSGGYEDDEDLGDEIIYTGHGGQDRSGVQIADQKLVNQNAALAQ…
A0A7X7WAE7 5-132 RAEIYKRSLIHEEYGGNRQSGISYPAKHYMVFIFTGFSGEEYGYNDRWENGYFLYYGEGQEGDMEFVRGNKAIRTHREKGKSLHLFQ…
A0A7X7BRR1 23-187 None
A0A1Y2HUK3 348-542 None
A0A4S2MIX3 120-284 None
A0A1C3F949 60-206 None
A0A803PYI2 7-157 None
A0A7J8IDA2 416-606 None
A0A6P5FLW4 50-219 None
A0A7N0UD35 236-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.