DPCstruct | MC8534

Metacluster Properties and Pfam Annotations

Number of structural domains580
Mean domain length (aa)166 ± 29 aa
Standard deviation of domain lengths29.48
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.57
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)12.74
Pfam Score73.88
Assigned Pfam label(s) CL0023- PF09536- CL0210- CL0161- PF12625

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C6YFZ1 6-164 ELSHAFVVARFYEELKSAFGNRGTEAFAHMTTVYARQRGSRMAQRAIRDGKPLDFTSYRIYGEWQKTEAAERVTGGFAGRTVSIAPD…
A0A1F9CNN5 9-155 YLEEGILAFAWYPEEDVLAILRALAKVSPDPGMDIYEFMGRTLARTNLGGVYAHLLRPGDPGGSLRLTSIIWGLYHDTGREVVVESG…
A0A1B2A221 11-150 None
A0A662TUE8 14-159 None
U1PRQ2 5-162 None
A0A1A8ZMR3 13-186 None
A0A7S2RK51 13-141 None
A0A523ASX4 113-269 None
A0A7W0VBE2 748-934 None
A0A7C5UP10 256-410 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.