DPCstruct | MC8527

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)96 ± 11 aa
Standard deviation of domain lengths10.85
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.09
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)41.52
Pfam Score75.00
Assigned Pfam label(s) CL0063- CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0RUM1 358-453 KPLALGSIKPAGWLRNELQLMSDGLAGHEHDFYDYVAHSLWLGGDKEYSGLNEGFPYWFNGIVPLAYGLDDERLMAQVRSSVQTVFE…
A0A179T028 1-104 MIGENLSELSLKPFTTNEIKPIGWLLRQLQIQAEGLSGNLDKFWPDIKESKWVGGDKEGWERVPYWLDGFIPLANGVGDQTLAFIFP…
A0A3D2WW81 37-131 None
A0A5N6FST0 1-99 None
A0A2V5I6X6 1-90 None
A0A0M2PFM8 1-95 None
A0A373IMQ4 24-100 None
A0A560J7L8 18-145 None
A0A7V4M312 44-149 None
I8A9V8 1-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.