DPCstruct | MC850

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)159 ± 18 aa
Standard deviation of domain lengths18.30
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score91.22
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)29.82
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1B9AL25 4-151 ENTMKFYGPPNEASPSYLIWYNNGPWKRTIAFRDEVPHDFPEPHSDVLEQFIDYHVPADKVGLVAQLEGSLVIDRTKGEVSVHCDNE…
A0A5C7JXL4 5-173 WKFNGAKEQLIFLTSLFGKSDTLAQQAGGSAKWTESLKDKKLFGLPICFSSYEVKDEEVYSLFPVEHFENQYASVIVNVEPATLEYL…
A0A424STS0 13-158 None
A0A7Y5TSW6 3-159 None
A0A4R5A9J1 431-594 None
A0A7V9SI00 1-135 None
A0A2E6W7R1 255-405 None
A0A0F9EH53 20-170 None
A0A846KX34 1-107 None
A0A4S8HLC3 26-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.