DPCstruct | MC8435

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)72 ± 9 aa
Standard deviation of domain lengths9.12
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.11
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)45.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H6SKP4 512-579 MSDSTKYLLPEEQMPKAWYNLAADFPQPVPPPLHPGTMKPVTPDDLAPIFPNAVIEQEMSLERWIDIP
A0A6V8K7H5 5-76 GTTNVLTMSEPTKILLDESEMPRRWYNVLADLPSPPPPVLHPGTLQPVGPDDLAPLFPMDLILQEVATDRYV
A0A0D2ZZB6 8-92 None
A0A140LB88 1-64 None
A0A151RHD1 1-79 None
A0A6G3VE23 10-68 None
A0A1Q9E6K1 264-348 None
N1QXX5 185-246 None
A0A7N0ZSY6 24-111 None
X1KDA1 1-65 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.