DPCstruct | MC8422

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)179 ± 20 aa
Standard deviation of domain lengths19.93
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score91.96
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)23.55
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S6HXD1 323-507 LPTYMWVSKAEQNLGNYLRFLSLQQVYWLRMAIQSELWNLSDAEYVMNRLMENPQDFQMAFKTFYGDENAKKLADLLTNHLTMVINY…
A9KQZ6 6-182 YEFTRRQLDLSNELRDLWQQHVLWTRSFIISTAASLGDLEPVTKRLMRNPTDFGNLFRLFYGRQTALEFEDLFTQHLQLAGELVNAL…
A0A7W1A924 18-206 None
A0A1G3XR97 35-249 None
A0A429Y529 3-159 None
A0A561PMW7 25-211 None
A0A6J6DA82 23-243 None
A0A2I0QSR2 151-337 None
A0A7Z0W1W5 99-277 None
A0A3E2N641 154-346 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.