DPCstruct | MC8415

Metacluster Properties and Pfam Annotations

Number of structural domains346
Mean domain length (aa)169 ± 38 aa
Standard deviation of domain lengths38.29
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.93
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)16.57
Pfam Score93.81
Assigned Pfam label(s) CL0023- PF02898- CL0090- CL0105- CL0091

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3EMD1 471-647 None
H3EMC0 555-727 None
H3EFT5 845-1007 None
A0A2G9UMU2 46-371 None
A0A2G9UCS8 9-145 None
A0A2E2IK50 13-164 None
A0A2M9PE03 25-160 None
A0A016TBZ7 27-272 None
A0A673WXP7 19-169 None
A0A673UEF0 4-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.