DPCstruct | MC8391

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)159 ± 18 aa
Standard deviation of domain lengths17.88
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score75.90
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)36.46
Pfam Score93.75
Assigned Pfam label(s) CL0266- PF12473

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G8JU44 1-123 MHVRPVAREKILNLTVPVFVDIREDDGRGSFSPIPRDNRCFKMRQGARKEIIVTIQPTNSKILNIERCFGVLICPGRNVPDRDLHLL…
A0A814C6Z4 1-179 MTTNSTYSGGRAEKTGTTLDSNHTNSTDENEIYHILLSFANAIKTAARPSQTQVQPHSKSSNLLVKFRAHLDIKEHDGKGNFEFVQR…
A0A0R3S3G7 127-299 None
A0A4Z2B5W3 212-361 None
A0A5K3FEH7 147-315 None
A0A0N5CMQ2 276-443 None
A0A6I9PV68 1-155 None
A0A815YXB4 269-408 None
A0A402EIY6 381-571 None
W2TCG4 158-306 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.