DPCstruct | MC8385

Metacluster Properties and Pfam Annotations

Number of structural domains315
Mean domain length (aa)150 ± 29 aa
Standard deviation of domain lengths29.38
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.10
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)12.49
Pfam Score85.08
Assigned Pfam label(s) CL0609- PF19739- CL0059- PF19384- PF14926

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C1NAH3 193-315 CALSNNRFCTVKTYKDESVVDLHESFEKGGEWIRKKGIRLTRGEWAALCAAMDEVTKACDVVSENDIDICDLSSLRKAKVGRYRGEV…
A0A813TVS7 8-156 RPDNGDRQQAGEEELATKTLHVQSKRFYLDVKQNRRGRFLKIAEVSAGGRKSRILMSMNVASELRDHLQTFNEHLDTLGEPSPNNAP…
E8U684 272-435 None
A0A847CDL9 27-179 None
A0A0D2MPT8 6-136 None
T1EDC4 4-186 None
R7Q859 115-252 None
A0A2M8TZV0 1-123 None
A0A2L2MPA4 1-122 None
A0A6V7TWS7 50-242 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.