DPCstruct | MC8376

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)174 ± 14 aa
Standard deviation of domain lengths13.81
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score62.67
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)50.73
Pfam Score100.00
Assigned Pfam label(s) PF04201

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E9GN36 4-150 SFMNLSLEEQEIKKEEWRKELAEVEYEIQTMRQVLTSKLRKSSELKRKLGITAWGEFSNDISQGLRNVKETSTFQTIEEKVEEVSKA…
A0A1I8Q6V4 1-175 MEELYNTGNTSPAASVASADIAAEFAALTVEEQERQRAEWSQELARVEEEINTLRTVLASKTRHASDLKRKLGITVWKEITDDMNQG…
A0A267G2D2 9-198 None
A0A1L8EEJ5 1-177 None
A0A6P4F7B2 4-160 None
T1KU26 5-211 None
A0A6I8VFP8 69-240 None
C1BQ62 9-182 None
A0A1J1IT97 178-339 None
A0A0P8XMT2 4-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.