DPCstruct | MC8354

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)139 ± 30 aa
Standard deviation of domain lengths30.33
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.51
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.58
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8L337 1-86 MDPFSNNPSLHKVFVTSFSKAQEQGIVPVGYGICEDEWENGVYPSFYHIRSGRKAGKELLVQLPDSIWQPRALAWAQAIDIYHNII
S8FFF8 70-208 DDWVEAWNAHAVSGRHHNNTPSVNSDDLVARIIADQESNIRHAPIKVARHANPFQDEASEETFWTVFNGAWDLAPASLPNHLKLHDA…
A0A0D2Q4D5 330-423 None
A0A0C9UDB0 26-150 None
A0A4Y9ZSJ5 152-301 None
A0A4Y9Y1N1 111-240 None
A0A4S8LHZ8 2-174 None
A0A0D7AWN6 20-235 None
J0WP09 2-114 None
A0A4S8LU03 1-165 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.