DPCstruct | MC8337

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)119 ± 8 aa
Standard deviation of domain lengths7.91
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.06
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)28.45
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7E4W9M1 198-312 DICDVVQAVHLLQSKDPQVVAVAKSTLQRDVQQHIRQPPSMELTQEYLNASTEGLFAPPFVSRSSMWTRLRLATRNLRKIMPMEWKC…
A0A2R7X5N0 4-127 LNSLCGIPKADEESDFALVDTAFKLLTSKDERVSSLAQSSLRNTLKDRSIQGGDLINPAVFLSGGTDGLRNRGSLPSNEWTRARRAS…
A0A7D9EYY9 375-499 None
A0A4Y2T9S6 67-192 None
A0A2R7VWR5 20-142 None
A0A4Y2P123 122-246 None
A0A7E4UTX5 1-99 None
A0A7D9JUA6 70-186 None
A0A2J7QFW2 160-269 None
A0A6S7JFZ7 100-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.