DPCstruct | MC8334

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)88 ± 7 aa
Standard deviation of domain lengths7.03
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.88
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)36.96
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D2A033 150-232 IKVPADTECTCGCPEKKKCLSDQKFDPILCKCVCTNKEEEEKCLEKLNMNFKWKSKDCTCGCKREKNCTTGTVWKREECRCVK
A0A2R7X3I4 20-106 DCNAFQVYRKDECKCVCTNIDEMNKCLEDNKLKSWDPADCTCQCRNVKECSTGYIYNKHTCSCEPEQRHRINGGYLSDSRGGYRGRQ
A0A834MSD9 135-232 None
A0A6G0YHB4 333-420 None
A0A1Y1NGC0 37-119 None
B4I6X8 1-84 None
C4WXM2 222-305 None
E9H9T1 236-337 None
A0A1I8PDP6 137-216 None
A0A5N4ANR9 246-337 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.