DPCstruct | MC8294

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)64 ± 10 aa
Standard deviation of domain lengths9.83
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score87.52
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)51.23
Pfam Score98.00
Assigned Pfam label(s) CL0123- CL0029

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6H5GE61 5-66 HFTPPPEAPVFRPGQDEFDDPISFIRKIRPEAEKFGICRIIPPENWRPPFSLDLNNFVFNPR
C1BWS2 1-59 MTQPRPNEFIAPPECPVFEPSWEEFADPFAYINKIRPIAEKTGICKVRPPKVSFFNKGI
A0A061F1H1 6-91 None
A0A8B6DN68 3-72 None
A0A6V7YDI6 12-80 None
A0A6J1X2E3 21-86 None
A0A199VV12 37-106 None
A0A7S2UMF3 53-122 None
A0A6I8SML2 1-67 None
A0A803J4M5 2-69 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.