DPCstruct | MC8290

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)308 ± 74 aa
Standard deviation of domain lengths74.28
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score66.36
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.29
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E2LWQ6 13-380 VKNAIFTVARFLNLDPEMEVFICLLGDDVLETLFGRVRMIGGHSPNCNIYELRYRMASAKNVDAIFRRHPEWEKQPRRLKLFRGRDT…
A0A0C3FLW0 13-279 AKLDHISPRSWRGDVTVKNVVLLTCWSEGRRTASSQLLHAGWTAPFDEMEKIGGFDMFCPLGENRMVLMDGLTEGERNEDDEETDIR…
R7SFJ0 32-318 None
A0A4S8M0B8 9-251 None
A0A4S8LKC1 551-848 None
A0A4V4HI01 54-363 None
A0A0B7FPE5 279-575 None
E2L6M8 2-221 None
A0A4Z0A828 2-269 None
V2WKC3 39-292 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.