DPCstruct | MC8231

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)368 ± 74 aa
Standard deviation of domain lengths73.77
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score67.64
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.40
Pfam Score87.59
Assigned Pfam label(s) PF15017- CL0167- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J4D5B4 2-283 TPGIQMELEKYRQKNPLEAVIRTVFTPVIREPADEDVIFVRKFASLTGDLQYLSKVDIECIALTRRLQIESGDTSKLRETPMTLKID…
Q4D153 52-387 VGTAIPAYQKGLLILDANAFIKGMDNFSDVADVLVTTPQVVAEVRDRAARELLSRFSQVLHVLEPSKEAIAAVVSVAEKTGDLGAMS…
A0A7I8K1Y6 1-364 None
A0A0D3CT80 1-235 None
A0A7S3G7P3 153-570 None
A0A2R6X669 227-527 None
A0A818SHL0 12-361 None
A0A2P6RLV5 57-436 None
A0A6D2L598 29-485 None
A0A2C6L027 1-376 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.