DPCstruct | MC8216

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)120 ± 17 aa
Standard deviation of domain lengths16.72
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score77.91
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)42.48
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7KGW0 13-117 MLEGVESALGLSKGSLPKPFYTRLQLWGAVFPTNTHGVPCIFDPFGRAGICGDWLLGSNIEAAVLSGIALANHIADYSQSPGTDPGE…
M1CMN3 1-126 MLEGVEKALGLSKSSLQKPFYTKLQLWGAALPTNTPGIPCIFDPRGRAGICGDWLLGSSLEAAALSGIALADQIADYFEQGGPCSDE…
A0A7S0S6U3 45-180 None
A0A1J6JW90 16-126 None
A0A0M0K3T1 203-363 None
A0A7S0GP95 15-125 None
A0A2H5PVB4 4-101 None
A0A2H5PUI9 280-400 None
V4S9X1 5-100 None
A0A2H5PUI2 166-296 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.