DPCstruct | MC8181

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)79 ± 8 aa
Standard deviation of domain lengths8.46
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score69.82
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)46.31
Pfam Score100.00
Assigned Pfam label(s) PF04418

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H5S8G9 1-64 MGKKSEDELSETFDRCLADTAVKIVSAGSVGLIAAAIFKRQFPLWLGTGMGFGMGIANCRHDMR
A0A0D2WWT3 9-99 ESKQQQQIASEAQLGAKWDRCFTNMLVHTGVGAGVGIVLSLIFFKRRMAPVYLSTGFAIGTAYQQCQDDFASARATGKVVRISEAAL…
A0A6P8V376 2-72 None
A0A194R4C4 1-81 None
A0A395IQE1 51-121 None
A0A6P7FHV9 1-70 None
A0A3P8T4A0 109-190 None
F4X8A2 1-71 None
J9ELN6 5-89 None
A0A427YIJ3 6-92 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.