DPCstruct | MC8175

Metacluster Properties and Pfam Annotations

Number of structural domains164
Mean domain length (aa)154 ± 28 aa
Standard deviation of domain lengths28.10
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score71.98
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)20.88
Pfam Score99.69
Assigned Pfam label(s) CL0323- PF04145

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S4QLB2 601-735 MHMLGFTFTGEETPCLVYLFQGWHLTDSVRFWGAWIVTVLAGIFAEWLVAVRRWEATWRPVPKAAVGRFSPRRIVRQAGRLMLYALT…
A0A0D2UDT0 1-152 MTFYWSSSVTILFDEWAPATMGEYFGALVAVFFLGVAYELTRFLAHSLDKSLLAQSARASNDHSVLIEKRHVNGSGSSRVNFGLFDQ…
A0A1Q9CJX2 14-192 None
A0A1Y2H9U7 227-419 None
A0A146HK07 50-206 None
W7B0I0 130-262 None
A0A7J6KYV4 350-491 None
A0A7J6LYW2 335-476 None
A0A1E7FY33 643-780 None
R1CZ96 399-560 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.