DPCstruct | MC8172

Metacluster Properties and Pfam Annotations

Number of structural domains96
Mean domain length (aa)105 ± 13 aa
Standard deviation of domain lengths12.66
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score93.87
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)34.91
Pfam Score100.00
Assigned Pfam label(s) CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X8Z845 14-127 DSYYGYRIHEITEMIVADMGNYAHGNQSIQHMIYLYNYVGAREKTDRHIAEVRERLYSSAPDGYPGDEDNGQTSAWYVLSALGFYPV…
A0A5M5DX79 604-711 GRIGAYWHGNEPCHHVAYLYNYLKEPWKCQKWVRTIVDRFYGDTPDALSGNDDCGQMSAWYMFNCIGFYPVAPSSNMYNIGSPCVEA…
A0A812M016 170-291 None
A0A066VAS3 112-222 None
A0A127Z6N7 362-462 None
A9WTL6 195-285 None
A0A1M5EPK2 573-685 None
A0A538Q9E4 289-385 None
H0EZP5 129-210 None
A0A834RNR3 184-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.