DPCstruct | MC8141

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)213 ± 14 aa
Standard deviation of domain lengths14.34
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.78
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)21.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395YED8 2-195 AQWYSEHIYPWIVSLIGRFFGIFPFSVAEFLLYAGILLLVGSLVRIIYRLIKKKADKKEGLRYLRRLGIIALILAALYMTNCGINYH…
A0A2V2GIJ0 143-357 FIMLCIGVLAGAVHLVLALSTRFSDFMSVTVSAALRFCLAKLTGVLPFSLAETLIFMLPAVIILLFVISNAYAASKRKWWRFFFSLL…
A0A1H5SZA6 67-292 None
A0A318N2K2 2-222 None
A0A7X6YXJ8 1-200 None
A0A2V2G700 87-312 None
E6UI57 3-226 None
A0A120MY66 2-227 None
A0A2V7V846 53-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.