DPCstruct | MC8086

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)135 ± 15 aa
Standard deviation of domain lengths15.42
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score84.08
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)19.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2B9X131 2-121 EHKWCYSYNGENFTGSLNTKDEAINEAIREYGSEHKVLYVGQSVDPSTHVSVDGLMDSMYESVTEQCGDYAESFLYQVDENHQAVLE…
A0A072YLV6 5-130 KCEEWIAEITDIDSEIWNSDIEGDIRKEVIKEGMKMAKEEGLVTFRIGRKIPVGIPSLDVDNILEDTYNQVYDEVGEVAESFLEDIT…
A0A542MA45 40-162 None
A0A1M2Z3X8 239-396 None
A0A5C8AD24 206-345 None
A0A248UI24 88-242 None
A0A257YLW7 9-155 None
G2IZ23 52-208 None
A0A3D5LBD2 88-205 None
A0A3P3DHH6 5-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.