DPCstruct | MC8070

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)109 ± 21 aa
Standard deviation of domain lengths21.18
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score75.28
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)37.16
Pfam Score90.32
Assigned Pfam label(s) PF00184- PF00220- PF19318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A8B6H0C8 4-87 GGACMSCGPELSGQCVGPDICCGPFGCYMGTLESSICQKENESTHPCEIQGAPCGSRGQGNCVTDGICCDSGACSYNAKCKTNN
A0A3B4F8U1 2-115 HVKNLGQGPKPSERKYKLRKPKNCMSCGPGDRGRCFGPSICCGEGLGCLLSSPETAHCVEENYLLTPCQAGGRPCGSEGGRCAASGL…
A0A1E1WVS0 1-106 None
A0A267G698 63-165 None
A0A1Y3BKM5 14-126 None
A0A162S7M6 26-150 None
G1SG33 1-135 None
A0A0K0E2C0 11-111 None
A0A1I8I0Z5 7-91 None
A0A7R9LLX7 1-91 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.