DPCstruct | MC8065

Metacluster Properties and Pfam Annotations

Number of structural domains1228
Mean domain length (aa)147 ± 26 aa
Standard deviation of domain lengths26.36
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score90.40
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)17.37
Pfam Score85.41
Assigned Pfam label(s) PF12535- CL0063- CL0536- CL0110- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4P0XWF0 17-194 GAVIGANVHIGPFCIVGANVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTV…
A0A6G3NS57 31-179 TSAGDPEARRAALAELLGELGEGAEIRPPLRVDYGHRITVGPRTFVNFGAVFLDVARITIGADVQMGPNVQLLTPTHPIDPEPRRAK…
A0A381E381 67-202 None
A0A5S6QLD8 675-787 None
A0A7J0G0H9 89-237 None
A0A819MZI3 121-336 None
A0A4V1XW52 576-712 None
A0A543NTB1 435-581 None
A0A7R9UEV4 173-305 None
A0A2R6EAE3 33-178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.