DPCstruct | MC8009

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)129 ± 8 aa
Standard deviation of domain lengths7.92
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score84.84
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.22
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y0IF24 175-304 EAPTQIERVILTDEDSAIAIDISSRRFTGTSGIDNILIQEGVSVEQLNLLGGEDNVHFAGNVSDYDVSSQGTTALFTHRETGAVVEM…
A0A1H6R1C1 4-128 KPNKAVLNGSNQDISLGFNASVVGSSGRESIQVASGVDVSITGGAGDRILLTGDAADYTFTQQGSNLLLTSGGHTITLAIGGELRLI…
A0A840B4H4 62-191 None
A0A839H9G0 6-130 None
A0A839HBI9 5-128 None
A0A839HFN9 108-233 None
A0A3D4XRX8 159-286 None
A0A219B834 15-155 None
A0A1G7NP61 657-791 None
A0A2T2RBL5 1-129 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.