DPCstruct | MC8006

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)186 ± 23 aa
Standard deviation of domain lengths22.55
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score79.10
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)18.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R0YLI8 109-302 VNVPDMDKSASLHVSDMRVPTEKQDKIFSLLITSKEYGVMRVGDARLSPSAVRLLQHEAFKKLGADGKPHDVTVYHFVIYQNMRAQL…
A0A1Y0I7L2 62-268 TIGCSIQKVIVNSPGLQESLEQSENLQIKDLRPEAEKDREIFSLFILSEAYGTSRQGDMTEPPPLRILQHRIYDKYVNEARLPEVKV…
A0A846N2T8 28-195 None
A0A1V3PZY1 2-182 None
A0A4Q8U0F8 14-198 None
A0A2E4QX17 14-237 None
A0A7I8ECF9 8-185 None
A0A5C8KWW0 1-198 None
A0A0R0CBL1 25-234 None
A0A0F3KXU4 2-178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.