DPCstruct | MC782

Metacluster Properties and Pfam Annotations

Number of structural domains349
Mean domain length (aa)111 ± 23 aa
Standard deviation of domain lengths22.92
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score82.57
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)25.27
Pfam Score84.72
Assigned Pfam label(s) CL0304- CL0123- CL0104- PF06189- CL0193

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W7WHM1 4-119 LRLTLRQLQIFVAVARSGSTTAASAEIALSQSATSSAVNELERLLSLRLFDRAGKRLLLNDNGRALLPRALALLDGAAGIEQMSRDG…
A0A2T5WCH6 355-427 IAERLRTFETVLQAQSFAEAATRLGTRASVVSTHIRDLENIVGAHLFNRTQTGAHPTAEAHRLWRSINSARKG
A0A518HN36 6-146 None
A0A0B8P0L4 2-117 None
A0A228QWC6 1-127 None
A0A228Q0K4 19-144 None
A0A0X8HEB9 3-113 None
A0A7C2JU71 1-96 None
A0A0B8P7J3 6-149 None
A0A848A6E2 1-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.