DPCstruct | MC778

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)89 ± 4 aa
Standard deviation of domain lengths3.73
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score76.86
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)46.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z5T1E9 28-120 QQNSSLSQRFQEIVDIVETLASDCKGNTYDLLSLLRILETLHRQIRSDMFEPSLPDTRKNLYEVLRDIEETGGWPYIERMKLQKFLE…
A0A1J0ABN9 4-98 PQLQAIQEAVRAVVQERQGDAVALLAVLRLLEFLHREIESGSFTVALPQTRQDLYDLLLDIETQGGWPYIYRRSLESLLVYIRKTET…
A0A354B110 2-83 None
A0A0P7YVX3 44-127 None
A0A2W4ZUX7 12-95 None
A0A6N8FVQ2 4-91 None
A0A3M9ZAD8 11-99 None
A0A7X3YQS7 1-89 None
Q2JJ91 1-87 None
A0A0V7ZR61 10-97 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.