DPCstruct | MC7686

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)53 ± 1 aa
Standard deviation of domain lengths1.13
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score91.34
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.97
Mean intra-cluster local Distance Difference Test score0.96
Mean intra-cluster sequence similarity (%)84.39
Pfam Score97.06
Assigned Pfam label(s) PF00223- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1NHN7 189-241 MPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSY
A0A453H6E5 1-53 MPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGIWM
A0A6A4N2W3 217-269 None
A0A7J9KP56 129-176 None
A0A396I2B3 1-52 None
A0A830C908 129-181 None
A0A453N3H7 16-68 None
A0A2G3D3G0 30-82 None
A0A1S4AEF0 70-122 None
A0A814RG48 359-411 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.