DPCstruct | MC7678

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)116 ± 8 aa
Standard deviation of domain lengths8.31
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score83.94
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)43.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446SD94 211-326 TWYKELDGVHFEIWCRVTEKQMSFRDALAEVCALNRFPLRQRRMEGALKRDYTMERLESEYHTCTAKVPPGTEKDKAKELIAKAVKN…
A0A453GTT2 7-109 YLAFVKDLDSVFFEIWKLVNRQQMSFRDAMEHVYKENPFPLRKRDLEHELSHPVSLGLEEEFRRCTEGISEECDLPRRYVHYARKKL…
A0A452XF46 59-179 None
A0A3L6SMQ6 76-190 None
C7IXL1 1-114 None
Q5JLF3 429-549 None
A0A0E0JU08 105-219 None
A0A446JWI7 160-272 None
A0A4U6U2X3 352-471 None
R7W6M7 261-378 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.