DPCstruct | MC76

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)121 ± 8 aa
Standard deviation of domain lengths7.87
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score82.56
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)22.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A098QV42 201-322 PLRFGQFLYYCRVISWDNLIGALLEQRRERVNFGTTAVDLGLLSSTGVQTLGRHLRPGIFIGVTAQNLGLLTTRDVQKVLAVQRSRS…
A0A3D2TKS0 20-134 MHFGEYLVRENILSAHQILKALDEQRKRRKFIPLLLVELGMMDDHRALKLCTISNEDHKDVLDIMREEGIISQQQSNRIRIARDKSG…
A0A5B9P684 5-128 None
A0A2M8B6A4 162-290 None
A0A517NVV3 20-134 None
A0A1F9LU89 165-287 None
A0A1G0XVT9 2-116 None
A0A2E3XUF0 2-125 None
A0A355G7B5 236-355 None
A0A1V5XML0 91-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.