DPCstruct | MC7445

Metacluster Properties and Pfam Annotations

Number of structural domains716
Mean domain length (aa)198 ± 38 aa
Standard deviation of domain lengths38.37
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.67
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.41
Mean intra-cluster sequence similarity (%)12.17
Pfam Score71.30
Assigned Pfam label(s) CL0047- CL0126- CL0071- CL0285- CL0490

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A831TUB2 33-229 ASEAAAIDRETGILISYLRLGDMSLPRPRGDPPAVSQEEALRRAREFLERVGVEPRAPWVLTEARYQDAGTIAFYTFLWRKYFHGLR…
A0A534T0E8 1-128 MSLKQGIVASAPKGKPISGKFEVEDGKLQLSVYTAKGGGFSEVVVDPRSGRVAKVEAIEGGEDLTAAKAQADAMTKAKTALGGAVDA…
A0A6N3F9B0 12-189 None
A0A318KQH4 8-229 None
W7ZJU5 12-185 None
W7ZST3 430-594 None
A0A1E7DTL9 59-241 None
A0A518AN43 14-208 None
A0A2R3MYW8 291-494 None
A0A099T2Q7 1-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.