DPCstruct | MC7412

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)317 ± 61 aa
Standard deviation of domain lengths60.61
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score74.62
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)18.70
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T2P1A1 2-174 VPANTQLPLIPVTDLELVIYFYNLVSRPMVALRLYARGWGPARITNALNKYRKPDPPYLRNTCTVKCNTAFRRGKEMYGEDWHEANH…
A0A1Y2M853 1-337 MARKHGQNEDAVFACRMHCSQSVKHLDKYHFLRPTLSDHPLHNMVSTITTRRIRNSRPSFGGAAPSSTIPFPRKGNMTAVEILTFLP…
A0A6A5TQP7 1-276 None
A0A6A6JWS6 193-455 None
A0A6A5TC31 6-329 None
A0A2T2NZP8 2-307 None
A0A2T2NZM3 19-248 None
A0A6A5TRL9 126-455 None
A0A364N4R6 600-928 None
A0A364N4I4 1-371 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.