DPCstruct | MC7393

Metacluster Properties and Pfam Annotations

Number of structural domains412
Mean domain length (aa)138 ± 21 aa
Standard deviation of domain lengths21.08
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.01
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.43
Pfam Score94.41
Assigned Pfam label(s) CL0274- PF15928- CL0123- CL0260- PF00334

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q4BHE5 7-144 NMERTFVAVKPDGVQRGLCGEIIKRLEQRGFRLVAAKFTQASEEHMKKHYLDLKDKPFYAGLCKYMSSGPVLATVWEGQNVVKLVRM…
A0A7J8HDK0 9-145 PQNTLALIKPHATHEQREEIFSIIKEAGFDITQMKEILLTKEQADKIYFKITNKDFYKDVLEILSEGPSVVMILTKWNAVSEWRRLM…
A0A812L8C4 148-274 None
A0A482VHA0 1-112 None
A0A839IIM2 3-130 None
A0A1E7FZD6 351-488 None
A0A317XS20 2-152 None
R6M2W8 489-635 None
A0A066VT68 10-170 None
A0A2G3CRZ0 8-102 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.