DPCstruct | MC7372

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)183 ± 32 aa
Standard deviation of domain lengths31.60
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score82.34
Mean fraction of residues predicted as intrinsically disordered0.64
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)25.75
Pfam Score100.00
Assigned Pfam label(s) PF15604

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A837JSS3 25-155 GLKCGTVEYHHKQKPNKVTDIRELKRQIRGQIRAFNRILKEDGMAGLKQRINNYNAALEREGRDYVKGLGPAGEGNVWLHEPDMRVG…
M1Q8E1 4-155 NYKTKFDSEEFARQLKDQEKGMNELTVHEYRENRNRFIDKGRAIEGNAYQQAARERALRDKIDELFEQGLTLKEAKTQANEWMKTQA…
A0A3S5FA95 89-263 None
A0A0C6G1F1 940-1124 None
A0A4V1V1A4 8-158 None
A0A6P0Q4C9 180-387 None
U2FSB3 395-593 None
A0A5A9EA88 2-116 None
A0A3A9VW67 414-611 None
A0A1M4S3B6 47-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.