DPCstruct | MC737

Metacluster Properties and Pfam Annotations

Number of structural domains590
Mean domain length (aa)198 ± 47 aa
Standard deviation of domain lengths46.60
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score82.30
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)14.76
Pfam Score82.79
Assigned Pfam label(s) PF12127- CL0137- PF16200- PF07059- PF01015

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T0QY19 5-192 VTVRTGTRAVVTVDGLVVAVLDPGRHRLPGRRSRRAVEVVDVRENLLLITSQEAAALDVPGVRFAIAVRLRTVDPVAFGTVSQSPLD…
A0A7C5VAR6 9-164 DNELARRQGGAVICRPQPLRLRWVFDQLATADAHVLEARFAASVRVANTDADRNMFFELLLCDRQSVTAQMLVEHFAPPLRAALTGL…
A0A1B0C7J1 280-490 None
M2RWV7 8-161 None
A0A6P8HKX5 6-142 None
A0A4R2JBZ8 193-486 None
A0A554IRU7 136-264 None
A0A838YEW1 2-159 None
A0A820C0Y9 23-120 None
A0A1Q9C764 1-275 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.