DPCstruct | MC7254

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)236 ± 48 aa
Standard deviation of domain lengths48.36
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score69.50
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.49
Pfam Score98.72
Assigned Pfam label(s) PF07765- PF08084

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4DU09 1-196 MDAKVKAMIKLIDEDTDSFARRAEMYYKKWPKLMKLVKEFYRAYRALAERYDHTTGELRQADRTMAEVFPNQVPYVLFGNSPSGSSA…
A0A2G9GID2 11-291 MKRAEPKKSHSSWWDSLISPKNSKWLQENLEEMDQHVKRMLKLIEEDADSFAKKAELYFKKRPELISLVEEFYQIYRSLAERYDHVT…
B9FAA7 1-240 None
A0A7N0UMF5 10-212 None
M7Z126 216-457 None
A0A200R3P8 1-255 None
F6GUA8 138-487 None
A0A166CEM3 2-218 None
A0A2K2DJY7 85-336 None
A0A7J9FKH6 1-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.