DPCstruct | MC7128

Metacluster Properties and Pfam Annotations

Number of structural domains1779
Mean domain length (aa)436 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.96
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)12.92
Pfam Score81.86
Assigned Pfam label(s) PF21436- CL0020- PF04081- CL0316- CL0329

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A525K0S1 61-391 VRQNWENVYETESDKFDRDAEGHPLPRLRPGQTEPIPGHPEYSTHPPGMALLVAPILYPFRHTEFVEPMAIVCSTFAVIIAFFLFRS…
A0A5Q4EDZ7 20-427 YATSVFFLSLAIFFWRLGAGHLQDWDEAIYAEVSKNIIERNDWMTLFWGDSPWFHKPPLFMWSTAVLFKIFGISEFSARAASAIAGI…
A0A1D9FJT3 57-479 None
A0A2D6PY26 183-630 None
A0A2R7YBE8 83-622 None
A0A1X6PFH3 12-425 None
A0A1G1A4F1 12-431 None
A0A1Q6XDR4 373-978 None
A0A7V2U8B2 41-497 None
A0A7S2S1W0 30-455 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.