DPCstruct | MC707

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)254 ± 25 aa
Standard deviation of domain lengths25.28
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.87
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.82
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A417Y7D2 177-416 GADAVRPAVQVDLPGTFFVDADLLEQVGLVRPPALAVDAPLYAGSLTANGVHLADEDSFRQAGDTHFAFVVPERANEDVVTIGQALE…
I4Z4L1 297-541 APIRIPRSFFFNTRCLVDLLGLHPQVERPQVSRERYLASAKRLGLHLVDSKQGFRRDGDVLFAWAVPEPAFEDIDVLAHLLRRGVLS…
A0A849U1N7 386-628 None
A0A1D9G531 4-207 None
A0A175WG83 623-853 None
Q2GTT9 285-574 None
A0A3N4KAU4 320-572 None
A0A4Q4YBH1 309-574 None
A0A2Z6RDG1 510-743 None
A0A835YPY8 96-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.