DPCstruct | MC705

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)89 ± 8 aa
Standard deviation of domain lengths7.63
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score80.47
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A433DD38 1-80 MLSNDIIDRLDYPVYWSRPHTEWGSIVDWDMFYIDQMPGSTLRDSHQALARDLNTLIDNLLTKSRECQKAKSLQALLNTQ
A0A433D512 31-120 RLSKELKGLLHYPEYWDRNASLWGDVVDWDIFFINKTPSCTAKSAHTALSSELDNLLENFPVGSFQHKKALALRAAIKVKFLIFSDK…
U9UEZ6 52-135 None
A0A2N1N6C3 2-89 None
A0A2H5SC57 1-86 None
A0A2Z6RGU7 27-123 None
A0A2I1EYJ4 1-82 None
A0A372Q4N2 2-83 None
A0A2N0QNT5 69-153 None
A0A397U0K0 4-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.