DPCstruct | MC6989

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)145 ± 21 aa
Standard deviation of domain lengths20.67
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score92.81
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)39.05
Pfam Score100.00
Assigned Pfam label(s) CL0254

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5M9K3I0 1-136 MRSYKKPEEVFDKTGKLLPELKELAPIGNARMSANPVGNGGILRKPLDIPDFRKYAFENIEPGVSNLPSMSNMAKLLRDVVAKNMHT…
X8AUE6 53-183 RSYRPQELFDTNGTLRAELRALAPNGNRRMSANPHANGGLLLRDLDLPDFRDYAVDVSRPATLTHEATKVLGTFLRDVIARNRDRFR…
A0A2P9IAH4 213-373 None
A0A6G3V8H9 36-172 None
A0A0D2EBX5 187-292 None
A0A2R5HE69 186-356 None
A0A449A3D7 108-237 None
K2PFW1 240-403 None
A0A8B3HHA1 2-118 None
A0A1V8UTK8 714-877 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.