DPCstruct | MC6988

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)160 ± 22 aa
Standard deviation of domain lengths22.24
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score70.68
Mean fraction of residues predicted as intrinsically disordered0.66
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)37.18
Pfam Score100.00
Assigned Pfam label(s) PF08432

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M2ZZV9 76-248 NVYTRRLVAEASAKACWICFKPSSTVLINEDQDFFYICPGHLTDPKFATAKDAEDLAKKKKDEEIEKEIEAVKKEFAEKMRKKMDRR…
A0A5M9K063 6-149 NIWTHRKVAETASKPCEICYKPSASVLITPENKDFFYVCPSHLKDKGFATPIIDEAALAAKKKKEMDDEIERVKQEFEEKQKRKKQK…
H0EQN3 1-135 None
A0A420Q319 2-144 None
A0A1Y2G452 11-216 None
A0A427YXA5 366-537 None
U7PW77 1-137 None
Q6C8I9 1-155 None
A5AAJ9 4-201 None
A0A0N1HDB2 1-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.