DPCstruct | MC6975

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)60 ± 3 aa
Standard deviation of domain lengths2.83
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score85.90
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)50.31
Pfam Score100.00
Assigned Pfam label(s) CL0193

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P6D8S9 10-64 DHSTSVKAKLNNHGTLGALLQHEVLPKSVVTVSSEIDTKALDKHPRFGLSLALKP
A0A2G3ACK3 19-76 KHQLDEVTTVEARLNNFGKATALFQRERPNFVLTLSGEIDTKALNKGAKFGWAVKMMG
A0A4S4EF19 252-317 None
A0A446U8C1 216-274 None
A0A2P5XV74 325-383 None
A0A816K1C7 543-601 None
A0A1R3IA83 8-67 None
A0A2U1PD92 428-486 None
D7SIG0 200-258 None
A0A7C9CWS9 63-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.