DPCstruct | MC6974

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)418 ± 109 aa
Standard deviation of domain lengths108.59
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.50
Pfam Score100.00
Assigned Pfam label(s) PF02724

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A497GWY5 24-478 SWDRALVVGHRDADGVTATAIALRTLEAMGIEAGYEIVQELSSQVLASLASRSVPIWFVDIGAGWLPQLRGLRFVLTDHHPPREAEI…
A0A2G3A7I5 2-442 VREQSIESFYTRLRDSALASASTSPLLVFPSTSDVDSLCALKIIGHVLESDSVRYACYPVSSFKEIYKYTGDNLGPAADEPITILLI…
A0A2A4K7M8 1-525 None
A0A835APH1 452-836 None
L1K0Q3 270-702 None
A0A1V9ZXW5 2-602 None
D3BKP9 161-765 None
A0A183H3U7 15-398 None
A0A6L5CT05 18-310 None
A0A1R4ABD1 1-522 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.