DPCstruct | MC6966

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)102 ± 6 aa
Standard deviation of domain lengths5.58
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score87.61
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)54.07
Pfam Score100.00
Assigned Pfam label(s) CL0163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2C5L3 304-403 AMDFIWYMWCGPDAPLFDKNKMATFERYFIADKELHKEKKGHYYTLRNQEDICNKILDEFGASGPHSHIINGHVPVKTIKGEQPIKA…
A0A7V8M7S1 1-104 MWYLWTGPNSPLFGKHDMTTFERYFISDPKAHVEGRNPYYHLRKDPEFIKKILAEFVLDPEVGHVINGHTPVKKGTDPIMANNKMIV…
A0A854XE81 82-185 None
A0A1V5VT59 2-97 None
A0A7E4S0E4 250-354 None
Q7P7U2 140-244 None
T0CYQ5 253-338 None
G9YJS3 20-124 None
C0BAN0 166-271 None
A0A645E0L8 51-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.