DPCstruct | MC6894

Metacluster Properties and Pfam Annotations

Number of structural domains88
Mean domain length (aa)259 ± 46 aa
Standard deviation of domain lengths46.47
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score80.44
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.83
Pfam Score84.94
Assigned Pfam label(s) CL0067- PF04998- PF05000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A149V9A9 71-251 GEIIEQPIIANFKEGLSVLDYFTSSHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEPDCGTERGLTVRAVMDSGEVVASLSER…
A0A2G2WJC4 117-356 MRGLMSDPQGQMIDLPIQSNLREGLSLTEYITSCYRARKGVVDTAVRTSDAGYLTRILVEVVQHIVVHRTDCGIAPGIFVSPRNGMM…
A0A396I5W7 19-265 None
A0A1Y4CZ42 282-585 None
A0A4S4E972 2-257 None
A0A0G1K9N5 211-545 None
A0A1V3WKY8 232-536 None
A0A059ADJ1 2-229 None
F3KFL6 101-275 None
Q20EX3 199-509 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.