DPCstruct | MC689

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)310 ± 39 aa
Standard deviation of domain lengths38.59
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score80.95
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)26.93
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J8IU70 5-276 PNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQ…
A0A315VQJ4 25-361 SMNSSSGRSTCQGSSSPLSGSVQQRKRLSFICDACKAKVQMVADLLLLSSETRPVMTSEGVALADTFDQCRDTVIARTKELSILTHD…
A0A183LSE6 2-382 None
A0A0K0EJV8 1399-1693 None
A0A183W1J9 20-309 None
A0A5K4FAM0 1546-1866 None
A0A183KPX6 3-380 None
A0A1S3PX09 490-782 None
A0A182EID8 566-859 None
H2NP07 26-290 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.